|
週次 |
日期 |
單元主題 |
|
第1週 |
2/15 |
[GenomMed] Genetics/Genomics in Medicine; Introduction to the Human Genome (Chapters 1, 2) (PL Chen)
[Bioinfo] Introduction to Human Genome Versions (SJ Hsu)
[Bioinfo] Introduction to Bioinformatics (CY Chen)
[NGS] Tools in Molecular Biology and Human Diseases: the Classic (PL Chen) |
|
第2週 |
2/22 |
[GenomMed] Genes; Genetic Diversity (Chapters 3, 4) (PL Chen)
[NGS/Bioinfo] Introduction to NGS / FastQC (HW1 NGS QC, Read Trimming) (SJ Hsu)
[NGS] Sequencing: the 1st-generation and the 1st 2nd-generation Platforms (PL Chen) |
|
第3週 |
3/01 |
[GenomMed] Clinical Cytogenetics; Chromosomal and Genomic Disorders (Chapters 5, 6) (PL Chen)
[NGS] Overview and History of NGS Technologies (PL Chen)
[NGS/Bioinfo] Sequence Alignment (BLAST) (CY Chen) |
|
第4週 |
3/08 |
[GenomMed] Mendelian, Complex and Mitochondrial Diseases (Chapters 7, 8) (PL Chen)
[NGS/Bioinfo] Multiple Sequence Alignment (HW2 Sequence Alignment - BLAST) (CY Chen)
[NGS] Must-know NGS Platforms: Illumina, PacBio, Nanopore and More (PL Chen) |
|
第5週 |
3/15 |
[GenomMed] Population Genetics and Genetic Mapping (Chapters 9, 10) (PL Chen)
[NGS/Bioinfo] SAM/BAM/CRAM, GATK Best Practices (SJ Hsu)
[Bioinfo/NGS] Variant Calling/VCF format, variant QC and sample QC (SJ Hsu) |
|
第6週 |
3/22 |
[GenomMed] Genetic, Molecular, Biochemical and Cellular Basis of Diseases (Chapters 11, 12) (PL Chen)
[Bioinfo/NGS] Variant Filtering (SJ Hsu)
[NGS/Bioinfo] Read Mapping Algorithms (CY Chen) |
|
第7週 |
3/29 |
[GenomMed] Treatment of Genetic Diseases; Developmental Genetics (Chapters 13, 14) (PL Chen)
[Bioinfo] Variant Annotation (SJ Hsu)
[GenomMed/NGS] Medical Sequencing (Targeted Panel, WES, WGS) (PL Chen) |
|
第8週 |
4/05 |
溫書假？清明連假？不上課 |
|
第9週 |
4/12 |
[GenomMed] Cancer Genetics and Genomics (Chapter 15) (PL Chen)
[Bioinfo] Genotyping and GWAS (CY Chen)
[Bioinfo] Functional Annotation (SJ Hsu) (HW3 Germline Single Nucleotide Variant & Insertion/Deletion Variant Discovery) |
|
第10週 |
4/19 |
[GenomMed] Genetic Counseling and Prenatal Diagnosis (Chapters 16, 17) (PL Chen)
[Bioinfo] Clustering (CY Chen)
[Bioinfo] Sequence Effect Predictors (SJ Hsu) |
|
第11週 |
4/26 |
Midterm |
|
第12週 |
5/03 |
[GenomMed/NGS] Library Preparation; Metagenomics (HY Li) (Invited Speaker)
[NGS] Biomarkers for Cancer Treatment (SJ Hsu)
[GenomMed/NGS] Phasing/Haplotyping/Pseudogenes/ME/SV/Immunogenomics (PL Chen) |
|
第13週 |
5/10 |
[GenomMed/NGS] RNA-seq (Wet-lab Perspective) (PL Chen)
[Bioinfo] Gene Expression Quantification (HW4 RNA-seq) (CY Chen)
[NGS] Single Cell RNA-seq and Spatial Gene Expression (PL Chen) |
|
第14週 |
5/17 |
[Bioinfo] DEG (differential analysis) (CY Chen)
[Bioinfo] Gene Set Enrichment Test (GSEA) (CY Chen)
[Bioinfo] Pathway Analysis and Interpretation (SJ Hsu) |
|
第15週 |
5/24 |
Final Project Proposal |
|
第16週 |
5/31 |
[GenomMed] Pharmaco-genomics & Precision Genomic Medicine; Ethical and Social Issues in Genomic Medicine (Chapters 18, 19)(PL Chen)
[GenomMed/Bioinfo] Biobanks & Data Sharing (SJ Hsu)
[NGS] Epigenetics (HC Tsai) (Invited Speaker) |
|
第17週 |
6/07 |
[GenomMed/NGS] What a Wonderful World! (ChIP-seq/ATAC-seq/Hi-C) (PL Chen)
[Bioinfo] ChIP-seq and DeepBind (CY Chen)
[Bioinfo] Protien Structure Prediction (CY Chen) |
|
第18週 |
6/14 |
Final Project Presentation |